IGF-1 LR3 (Long-R3 Insulin-Like Growth Factor 1) is a synthetic 83-amino acid analog of native IGF-1, engineered with an arginine substitution at position 3 and a 13-amino acid N-terminal extension. These modifications reduce its binding affinity to IGF-binding proteins, extending its functional half-life in research models.

In research models, IGF-1 LR3 has been studied for its activity at the IGF-1 receptor and downstream signaling pathways including PI3K/Akt and MAPK cascades. Investigations have explored its effects on cellular proliferation, protein synthesis pathways, and glucose-related signaling at the cellular level.

IGF-1 LR3 has also been examined in research contexts focused on muscle cell signaling, tissue growth pathways, and metabolic regulation. Published studies have characterized its extended pharmacokinetic behavior compared to native IGF-1, receptor binding affinity, and downstream cellular effects across multiple research designs.

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Product Notes

– Product: IGF-1 LR3 (Long-R3 Insulin-Like Growth Factor 1)
– Strength: 0.1mg or 1.0mg per vial (select strength)
– Storage: Store lyophilized vial refrigerated; reconstituted vial refrigerated and used within researcher-determined timeframe
– Category: Neuroendocrine / Growth Signaling
– Intended Positioning: Research Use Only

For Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.